What is Government Decree No 359 / 2021 Coll.?

Government Regulation No 359 / 2021 Coll., amending Government Regulation No. 454 / 2009 Coll., establishing, for the purposes of the Criminal Code, what is considered to be substances with anabolic and other hormonal effects and what is the greater quantity of substances and what is considered to be a method for the purposes of the Criminal Code to increase oxygen transmission in the human organism and other methods with doping effect, as amended by Government Regulation No. 2 / 2012 Coll. — Government Regulation amending Government Regulation No. 454 / 2009 Coll., establishing, for the purposes of the Criminal Code, what is considered to be anabolic and other hormonal substances and what is the greater quantity of them and what is considered to be a method for the purposes of the Criminal Code to increase oxygen transmission in the human organism and other methods with doping effect, as amended by Government Regulation No. 2 / 2012 Coll..

When it became Government Decree No 359 / 2021 Coll. effectiveness?

Government Decree No 359 / 2021 Coll. became effective 01.01.2022.

Is Government Decree No 359 / 2021 Coll. still valid?

Yes, Government Decree No 359 / 2021 Coll. is still valid and effective.

How many times was it Government Decree No 359 / 2021 Coll. amended?

Government Decree No 359 / 2021 Coll. has 3 time versions of the text.

Government Decree No 359 / 2021 Coll.

Government Regulation amending Government Regulation No. 454 / 2009 Coll., establishing, for the purposes of the Criminal Code, what is considered to be anabolic and other hormonal substances and what is the greater quantity of them and what is considered to be a method for the purposes of the Criminal Code to increase oxygen transmission in the human organism and other methods with doping effect, as amended by Government Regulation No. 2 / 2012 Coll.

Valid Regulation Effective from 01.01.2022

Text versions: 01.01.2022 04.10.2021

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359

GOVERNMENT REGULATION

of 20 September 2021

amending Government Regulation No. 454 / 2009 Coll., laying down for the purposes of the Criminal Code what is considered to be substances with anabolic and other hormonal effects and what is the larger quantity of substances and what is considered to be a method for the purposes of the Criminal Code to increase oxygen transmission in the human organism and other methods with doping effect, as amended by Government Regulation No. 2 / 2012 Coll.

The Government orders pursuant to § 289 (4) of Act No. 40 / 2009 Coll., criminal code:

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Government Regulation No. 454 / 2009 Coll., establishing, for the purposes of the Criminal Code, what is considered as anabolic and other hormonal substances and what is the larger quantity of them and what is considered as a method for the purposes of the Criminal Code to increase oxygen transmission in the human organism and other methods with doping effect, as amended by Government Regulation No. 2 / 2012 Coll., is amended as follows:

1. Annex No 1, including the title, reads:

"Annex No 1 to Government Regulation No 454 / 2009 Coll.

Anabolic and other hormonal agents

A. ANABOLIC SUBSTANCES

A.1 Androgenic anabolic steroids (AAS)

(a) exogenous AAS

1.1-androstenediol (5a-androst-1-en-3b, 17b-diol);

2.1-androstendione (5a-androst-1-en-3,17-dione);

3.1-testosterone (17b-hydroxy-5a-androst-1-en-3-one);

4.4-hydroxytestosterone (4,17b-dihydroxyandrost-4-en-3-one);

5.19-norandrostendione (estr-4-en-3,17-dione);

6. bolandiol (19-norandrostendiol);

7. Bolasterone;

8. boldenone;

9. boldione (androsta-1,4-dien-3,17-dione);

10. danazol (17aethenyl-17b- hydroxyandrost-4-eno [2,3-d] isoxazole);

11. dehydrochloromethyl testosterone (4-chloro-17b-hydroxy-17a-methylandrosta-1,4-dien-3one);

12. desoxymethyltestosterone (17amethyl-5a-androst-2-en-17bol);

13. Drostanolone;

14. estra-4,9-dien-3,17-dione (19-norandrosta-4,9-dien-3,17-dione);

15. ethyl estrenol (19-nor-17a-pregn-4-en-17-ol);

16. fluoxymesterone;

17. formebolone;

18. furazabol (17b-hydroxy-17a-methyl-5a-androstano [2,3-c] -furazan);

19. Gestrinone;

20. calusterone;

21. clostebol;

22. mestanolone;

23. mesterolone;

24. methanedienone (17b- hydroxy- 17a- methylandrosta-1,4-dien-3-one);

25. Methandriol;

26. methasterone (2a, 17adimethyl-5a-androstan-3-one-17bol);

27. methenolone;

28. methyl-1-testosterone (17b-hydroxy-17a-methyl-5-androst-1-en-3-one);

29. methyldienolone (17b- hydroxy- 17a- methyl-4,9-dien-3-one);

30. methylnortestosterone (17b- hydroxy- 17a-methyl-str-4-en-3-one);

31. methyltestosterone;

32. methyltrienolone (17b- hydroxy- 17a- methyl-4,9,11-trien-3-one);

33. mibolerone;

34. nandrolone;

35th norboletone;

36. norclostebol;

37. norethandrolone;

38. oxabolone;

39. oxandrolone;

40. oxymesterone;

41. oxymetholone;

42. prostanozole ([3,2-c] pyrazol-5a-etioallocholan-17btetrahydropyranol);

43rd quinbolone;

44. stanozolol;

45. stenbolone;

46. tetrahydrogestrinone (18ahomopregna-4,9,11-trien--17bol-3-one);

47th Trenbolone;

48. other substances with similar chemical structure or similar biological effects;

(b) endogenous AAS

1.4-androstendiol (androst-4-en-3b, 17b-diol);

2.5-androstendione (androst-5-en-3, 17-dione);

3.19-norandrosterone;

4.19-noretiocholanolone;

6.3b-hydroxy-5a-androstan-17-one;

7.5aandrostan-3a, 17adiol;

8.5.a.androstan-3a, 17b-diol;

9.5aandrostan-3b, 17adiol;

10.5aandrostan-3b, 17bdiol;

11. androst-4-en-3a, 17adiol;

12. androst-4-en-3a, 17b-diol;

13. androst-5-en-3a, 17adiol;

14. androst-5-en-3a, 17b-diol;

15. androst-5-en-3b, 17adiol;

16. androstendiol (androst-5-en-3b, 17b-diol);

17. androstendione (androst-4-en-3, 17-dione);

18. Dihydrotestosterone;

19. Epidihydrotestosterone;

20. Prasterone (dehydroepiandrosterone DHEA);

21. testosterone;

22. other substances with similar chemical structure or similar biological effects.

A.2 Other anabolic agents

1. clenbuterol;

2. selective androgen receptor modulators (SARM), for example:

2.1 ligandrole (LGD-40233);

3. tibolone;

4. zeranol;

5. zilpaterol;

6. other substances with similar chemical structure or similar biological effects.

B. PEPTIDE HORMONES, GROWTH FACTORS, COMPOUNDS AND MIMETIC

erythropoiesis stimulating agents

(a) erythropoietin receptor agonists such as:

1. darbepoetins (dEPO);

2. erythropoietins (EPO);

3. compounds based on EPO, for example:

3.1 EPO-Fc;

3.2 methoxypolyethylene glycol-epoetin beta (CERA);

4. EPO- mimetic agents and their compounds, for example:

4.1 CNTO 530;

4.2 peginatide;

(b) the activation means of the factor-inducing hypoxia (HIF), such as:

1. daprodustat (GSK1278863);

2. IOX2 molidustat (BAY 85-3934);

3. roxadustat (FG-4592);

4. vadudustat (AKB-6548);

1. K-11706;

(d) transforming growth factor beta (TGF - β) signaling inhibitors such as:

1. lupatercept;

2. sotatercept.

B.2 Peptide hormones and their release factors

(a) choriogonadotropin (CG) and luteinisation hormone (LH) and their release factors

1. buserelin;

2. deslorelin;

3. gonadoreline;

4. goserelin;

5. leuprorelin;

6. nafarelin;

7. triptorelin;

(b) corticosteroids, their release factors;

1. growth hormone fragments, for example:

1.1 AOD- 9604;

1.2 hGH 176-191;

2. Growth hormone release hormone (GHRH) and its analogues, such as:

2.1 CJC-1293;

2.2 CJC-1295;

2.3. CJC-1295 DAC;

2.4. Dumorelin;

2.5 rismorelin;

2.6 sermorelin;

2.7 somatorelin;

2.8. Tesamorelin;

(d) growth hormone secretion (GHS) and ghrelin receptor agonists, such as:

1. anamorelin;

2. ibutamoren (MK-677);

3. ipamorelin (NNC 26-0161);

4. lenomorelin (ghrelin);

5. macimorelin;

6. tabimorelin;

(e) releasing peptides of growth hormone GH (GHRP), such as:

1. alexamorelin;

2. examorelin (hexarelin);

3.GHRP-1;

4.GHRP-2 (pralmorelin);

5.GHRP-3;

6. GHRP-4;

7. GHRP-5;

8.GHRP-6;

(f) other substances with similar chemical structure or similar biological effects.

Growth factors and growth factor modulators

(a) fibroblaster growth factors (FGF);

(b) hepatocyte growth factor (HGF);

(d) mechanical growth factors (MGF);

(e) platelet growth factor (PDGF);

(f) thymosine-β4 and its derivatives, such as:

1. TB-500;

(g) vascular-endothelial growth factor (VEGF);

(h) other substances with similar chemical structure or similar biological effects.

C. HORMON AND METABOLIC MODULATORS

C.1 Flavourings inhibitors

1. aminoglutethimide;

2. Anastrozole;

3. exemestane;

4. formestane;

6. testosterone;

7. other substances with similar chemical structure or similar biological effects.

C.2 Selective oestrogen receptor modulators (SERM)

1. raloxifene;

2. Tamoxifene;

3. toremifene;

4. other substances with similar chemical structure or similar biological effects.

C.3 Other antiestrogenic substances

1. cyclofenil;

2. fulvestrant;

3. clomiphene;

4. other substances with similar chemical structure or similar biological effects.

C.4 Substances modifying the function of myostat including myostat inhibitors

C.5 Metabolic modulators

(a) AMP-activated proteinkinase (AMPK) activators such as:

1. AICAR;

(b) receptor agonists delta activated by peroxisome proliferators (PPARδ), such as:

1. cardarin (GW1516, GW501516, endurobol);

(d) meldonium;

(e) Rev-ErbA agonists, for example:

1. Stenabolic (SR9009);

(f) other substances with similar chemical structure or similar biological effects.

C.6 Hormones stimulating melanocytes

(a) synthetic analogues of α-MSH, for example:

1. bremelanotide;

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Regulation Information

Citation	Government Regulation No 359 / 2021 Coll., amending Government Regulation No. 454 / 2009 Coll., establishing, for the purposes of the Criminal Code, what is considered to be substances with anabolic and other hormonal effects and what is the greater quantity of substances and what is considered to be a method for the purposes of the Criminal Code to increase oxygen transmission in the human organism and other methods with doping effect, as amended by Government Regulation No. 2 / 2012 Coll.
Regulation Type	Regulation
Author	-
Collection	Code of Laws

Date of Promulgation	04.10.2021
Effective from	01.01.2022
Effective until	-
Status	Valid

Legal Areas: Administrative law Criminal law Criminal law substantive Health

The regulation text is for informational purposes only.

Government Decree No 359 / 2021 Coll.

Contents

Čl. I

Contents

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Regulation Information

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